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SABRE : Cutting Edge Genomics for Sustainable Animal Breeding
an EU INTEGRATED PROJECT (SIXTH FRAMEWORK PROGRAMME, PRIORITY 5 Food Quality and Safety)

SABRE provides fundamental knowledge of the genomics and epigenetics of animal health, food safety and food quality traits of livestock species, together with strategies to deliver such technologies for use in selection. This will enable producers to move animal breeding and production towards more sustainable, environmentally and welfare friendly, low-input systems, that deliver safe and high quality foods in line with consumer expectations and European Policy.

To determine the origin of genetic variation in key quality safety, health and sustainability traits in real world livestock populations, SABRE combines the power of  gene mapping technologies is with gene expression studies in target tissues and modern bioinformatics tools with available and expanded genome sequences.

Research is clustered in three areas:
1) development of underpinning technologies and knowledge, including mathematical genomics, epigenetics and sequencing,
2) understanding of the genomics of key biological systems concentrating on fertility, mammary function and the intestine,
3) tackling focused breeding goals including meat quality, reduced incidence of zoonotic infection and improved animal well-being.

SABRE Work Package 6 is about female fertility and focuses on the identification of genes that are involved in female sexual behaviour, folliculogenesis, embryonic developmental competence and, more general, conception rate.